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A blood-based multi-pathway biomarker assay for early detection and staging of Alzheimer's disease across ethnic groups.Jiang Y., Uhm H, Ip F.C.F., Ouyang L., Lo RMN, Cheng E.Y.L., Cao X., Tan C.M.C., Law B.C.H., Ortiz-Romero P., Puig-Pijoan A., Fernández-Lebrero A., Contador J., Mok K.Y., Hardy J., Kwok T.C.Y., Mok V.C.T., Suárez-Calvet M., Zetterberg H., Fu A.K.Y. and Ip N.Y.
Alzheimers Dement. 2024 Jan 6. doi: 10.1002/alz.13676. PMID: 38183344
[Abstract] [Full text] The VCAM1–ApoE pathway directs microglial chemotaxis and alleviates Alzheimer’s disease pathologyLau S.F., Wu W., Wong H.Y., Ouyang L., Qiao Y., Xu J., Lau H.Y.J., Wong C., Jiang Y., Holtzman D.M., Fu A.K.Y. and Ip N.Y.
Nature Aging 2023 Sep 21. doi: 10.1038/s43587-023-00491-1.
[Abstract] [Full text] [ALZFORUM] Does Plaque ApoE Summon Microglia to Amyloid? [Nature Review Neurology] ApoE attracts microglia to amyloid-β plaques Deep learning-based polygenic risk analysis for Alzheimer's disease predictionZhou X., Chen Y., Ip F.C.F., Jiang Y., Cao H., Zhong H., Chen J., Ye T., Chen Y., Zhang Y., Ma S., Lo M.N.R., Tong P.S.E., Alzheimer’s Disease Neuroimaging Initiative, Mok C.T.V., Kwok C.T.V., Guo Q., Mok K.Y., Shoai M., Hardy J., Chen L., Fu A.K.Y. and Ip N.Y.
Commun Med (Lond) 2023; 3: 49. doi: 10.1038/s43856-023-00269-x
[Abstract] [Full text] [The Croucher Foundation] Deep-learning AI could predict Alzheimer's risk
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